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Rheumatology Advance Access originally published online on January 31, 2008
Rheumatology 2008 47(3):380-381; doi:10.1093/rheumatology/kem330
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Crohn's disease, relapsing polychondritis and epidermolysis bullosa acquisita: an immune-mediated inflammatory syndrome

E. F. Vicente1, A. Hernández-Núñez2, J. Aspa3, M. Aragües2 and R. García-Vicuña1

1Department of Rheumatology, 2Department of Dermatology and 3Department of Pneumology, Hospital Universitario de la Princesa, Madrid, Spain

Correspondence to: E. F. Vicente, Department of Rheumatology, Hospital Universitario de la Princesa, C/Diego de León 62, 28006 Madrid, Spain. E-mail: evicenter.hlpr@salud.madrid.org

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SIR, We report the case of a 22-yr-old Caucasian woman admitted to hospital due to frank haemoptysis associated with cutaneous lesions in hands and feet, congestion of the upper airway tract, episcleritis and impaired phonation. She had a 2-yr history of Crohn's disease (CD), diagnosed by colonoscopy and intestinal biopsy, in remission under methotrexate treatment (12.5 mg/week). She referred progressive association of bilateral eyelid retraction with epifora, nasal congestion with saddle nose deformity and recurrent episodes of skin eruption associated with trauma . . . [Full Text of this Article]


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