Rheumatology Advance Access originally published online on July 7, 2008
Rheumatology 2008 47(9):1432-1433; doi:10.1093/rheumatology/ken243
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Repairing erosions in rheumatoid arthritis. A realistic goal
1Department of Rheumatology, Puerta de Hierro University Hospital, Madrid, Spain
Correspondence to: J.-L. Andreu, Servicio de Reumatología, Hospital Universitario Puerta de Hierro San Martín de Porres 4, 28035, Madrid. E-mail: jlandreu@arrakis.es
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SIR, Persistent inflammation in RA is an osteodestructive process, which leads to an accumulation of joint damage over time. Bone loss in RA occurs both in the joints and throughout the skeleton as a result of the multifactorial increase in bone resorption. Bone erosion starts early in disease and progresses most rapidly during the first year. The structural joint damage that is evident on conventional radiographs