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Rheumatology Advance Access originally published online on November 26, 2008
Rheumatology 2009 48(2):195-197; doi:10.1093/rheumatology/ken416
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

LETTERS TO THE EDITOR

The effect of calcium supplementation on serum urate: analysis of a randomized controlled trial

N. Dalbeth1, A. Horne1, G. D. Gamble1, R. Ames1, B. Mason1, F. M. McQueen1, M. J. Bolland1, A. Grey1 and I. R. Reid1

1Bone Research Group, Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand

Correspondence to: N. Dalbeth, Bone Research Group, Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Rd, Grafton, Auckland, New Zealand. E-mail: n.dalbeth@auckland.ac.nz

The first 10% of the full text of this article appears below.

SIR, Observational studies have shown an inverse relationship between ingestion of dairy products and hyperuricaemia/gout [1]. Intervention studies have also shown that ingestion of dairy products has a short-term urate-lowering effect, and that a dairy-free diet leads to increased serum urate concentrations, by a magnitude of ~0.06 mmol/l [2, 3].

Although dairy products are the principal dietary source of calcium, none of these studies have specifically assessed the influence of dietary calcium intake. Previous reports have implicated calcium metabolism in the regulation of serum . . . [Full Text of this Article]


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