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Rheumatology Advance Access originally published online on February 20, 2009
Rheumatology 2009 48(5):592-594; doi:10.1093/rheumatology/kep017
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© The Author 2009. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Non-infectious endocarditis in a patient with cANCA-associated small vessel vasculitis

Taro Horino1, Toshihiro Takao2, Yoshinori Taniguchi1 and Yoshio Terada1

1Department of Endocrinology, Metabolism and Nephrology and 2Division of Community Medicine, Department of Community Nursing, Kochi Medical School, Kochi, Japan

Correspondence to: Taro Horino, Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kohasu, Okoh-cho, Nankoku, Kochi 783-8505, Japan. E-mail: horinott@yahoo.co.jp

The first 10% of the full text of this article appears below.

SIR, ANCAs are frequently associated with a limited group of small vessel vasculitic syndromes, referred to as ANCA-associated small vessel vasculitis (ANCA-associated SVV) [1]. ANCA-associated SVV is the most common primary systemic small vessel vasculitis in adults and includes three categories: WG, microscopic polyangiitis and Churg–Strauss syndrome [1].

Non-infectious cardiac involvement in ANCA-associated SVV is more frequent than it is thought [2]. However, both ANCA-associated SVV with endocardial compromise and subacute bacterial endocarditis (SBE) have the many overlapped clinical manifestations including detectable vegetations by cardioechography, inflammatory signs, renal involvement and constitutional symptoms. In addition, streptococcal SBE sometimes shows positive cANCA testing [3]. Here we report a case of non-infectious endocarditis with ANCA-associated SVV, which could be diagnosed in early stage by . . . [Full Text of this Article]


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