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Rheumatology Advance Access originally published online on May 14, 2009
Rheumatology 2009 48(7):853-854; doi:10.1093/rheumatology/kep115
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© The Author 2009. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

LETTERS TO THE EDITOR

High-resolution SPECT imaging of bony pathology in early arthritis of finger joints

Benedikt Ostendorf1, Andreas Wirrwar2, Katalin Mattes-György2, Christof Iking-Konert1, Dirk Blondin3, Ulrich Mödder3, Hans-Wilhelm Müller2, Matthias Schneider1 and Axel Scherer3

1Rheumatology, Department of Endocrinology, Diabetology and Rheumatology,2Department of Nuclear Medicine and 3Institute of Radiology, Heinrich-Heine-University, Düsseldorf, Germany

Correspondence to: Benedikt Ostendorf, Rheumatology, Department of Endocrinology, Diabetology and Rheumatology, Heinrich-Heine-University of Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany. E-mail: ostendorf@med.uni-duesseldorf.de

The first 10% of the full text of this article appears below.

SIR, We developed a multipinhole SPECT (MPH-SPECT) imaging system with up to 20 pinholes leading to a spatial resolution <1 mm and increased sensitivity by a factor of up to 50 compared with conventional bone scintigraphy (BS) [1]. Recently, we have demonstrated that MPH-SPECT represents a feasible tool for the study of osseous alterations in IL-1 receptor antagonist-deficient mice [2].

We report herein an initial clinical study with this newly developed method by imaging the clinically dominant hand of 13 early RA patients (ERA group, disease . . . [Full Text of this Article]


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