© The Author 2009. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Editorial |
Progress in systemic sclerosis: a 10-year perspective
1Royal Free and University College Medical School, London, UK, 2Department of Biomedicine, Centre DenoThe, Division of Rheumatology, AOUC University of Florence, Florence, Italy and 3Department of Internal Medicine and Immunopathology, Hospital Cochin, Paris, France
Correspondence to: C. M. Black, Centre for Rheumatology, Hampstead Campus, Rowland Hill Street, Hampstead, London NW3 2PF, UK. E-mail: profblack@btinternet.com
| The first 10% of the full text of this article appears below. |
SSc is a chronic CTD that affects the skin and internal organs, and is characterized by excessive fibrosis, inflammation and vasculopathy [1–3]. The progressive occlusive vasculopathy is central to the clinical manifestations of SSc and is reflected in its characteristic complications, which include renal crisis, digital ulceration and pulmonary arterial hypertension (PAH) [4]. These