Skip Navigation



Rheumatology Advance Access published online on April 16, 2003
Rheumatology, doi:10.1093/rheumatology/keg289
Rheumatology © British Society for Rheumatology 2003; all rights reserved
This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
42/9/1050    most recent
keg289v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Tench, C. M.
Right arrow Articles by D'Cruz, D. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Tench, C. M.
Right arrow Articles by D'Cruz, D. P.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 2003 British Society for Rheumatology2003; all rights reserved

Original Papers

Fatigue in systemic lupus erythematosus: a randomized controlled trial of exercise

C. M. Tench 1*, J. McCarthy 2, I. McCurdie 3, P. D. White 4, D. P. D'Cruz 1

1 Bone and Joint Research Unit
2 National Sports Medicine Institute
3 Barts and The London NHS Trust, London, UK
4 Department of Psychological Medicine, Barts and The London, Queen Mary's School of Medicine and Dentistry

* Corresponding author. E-mail: colin.tench3{at}which.net.

Received 29 April 2002 ; accepted 28 January 2003

Abstract

Objective. To test the efficacy of a graded aerobic exercise programme in treating fatigue in systemic lupus erythematosus.

Methods. Ninety-three patients with systemic lupus erythematosus without active disease in any major organ were randomized, using a minimization protocol, to 12 weeks of graded exercise therapy, relaxation therapy or no intervention.

Results. Analysis by intention to treat showed that 16 of the 33 (49%) patients in the exercise group rated themselves as ‘much' or ‘very much' better compared with eight out of 29 (28%) in the relaxation group and five out of 32 (16%) in the control group ({chi}2=8.3, df=2, P=0.02). Fatigue improved significantly on one out of three measures after exercise therapy and there was a trend for fatigue to improve on all measures after exercise.

Conclusion. These findings support the use of appropriately prescribed graded aerobic exercise in the management of patients with fatigue and systemic lupus erythematosus.

Key words: Fatigue, Exercise, SLE, Randomized controlled trial.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Adv. Psychiatr. Treat.Home page
A. Mak, R. C. M. Ho, and C. S. Lau
Clinical implications of neuropsychiatric systemic lupus erythematosus
Adv. Psychiatr. Treat., November 1, 2009; 15(6): 451 - 458.
[Abstract] [Full Text] [PDF]

Home page
 Rheumatology (Oxford)Home page
S. Y. Yuen and J. E. Pope
Learning from past mistakes: assessing trial quality, power and eligibility in non-renal systemic lupus erythematosus randomized controlled trials
Rheumatology, September 1, 2008; 47(9): 1367 - 1372.
[Abstract] [Full Text] [PDF]

Home page
 Rheumatology (Oxford)Home page
B. E. Strombeck, E. Theander, and L. T. H. Jacobsson
Effects of exercise on aerobic capacity and fatigue in women with primary Sjogren's syndrome
Rheumatology, May 1, 2007; 46(5): 868 - 871.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.