Skip Navigation



Rheumatology Advance Access published online on April 19, 2005
Rheumatology, doi:10.1093/rheumatology/keh664
This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
44/8/1012    most recent
keh664v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Ringleb, P. A.
Right arrow Articles by Schwaninger, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ringleb, P. A.
Right arrow Articles by Schwaninger, M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2005. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org
Received December 16, 2004
Accepted March 29, 2005

Original Papers

Cerebrovascular manifestations of Takayasu arteritis in Europe

P. A. Ringleb 1, E. I. Strittmatter 1, M. Loewer 2, M. Hartmann 2, J. B. Fiebach 2, C. Lichy 2, R. Weber 2, C. Jacobi 2, K. Amendt 3, and M. Schwaninger 2*

1 These authors contributed equally to this work; Department of Neurology, University of Heidelberg, Mannheim, Germany
2 Department of Neurology, University of Heidelberg, Mannheim, Germany
3 Diakonie Krankenhaus, Mannheim, Germany

* To whom correspondence should be addressed.
M. Schwaninger, E-mail: markus.schwaninger{at}med.uni-heidelberg.de


  Abstract

Objectives. Takayasu arteritis is well known as a cause of stroke in Asia but has rarely been described in the Western world. Here we report the clinical and neuroimaging follow-up of a series of patients with Takayasu arteritis from Europe.

Methods. Seventeen consecutive patients who fulfilled the diagnostic criteria for Takayasu arteritis of the American College of Rheumatology were evaluated on follow-up by standardized neurological examination, sonography and MRI.

Results. At follow-up almost 20 yr after onset of symptoms, the subclavian artery and the common carotid artery were often affected. In addition, evidence of intracranial pathology was found in seven patients. In contrast to the severe vessel involvement, the neurological state was stable. Two patients had suffered from stroke before the diagnosis was made and therapy was initiated, and one patient had recurrent transient ischaemic attacks. Intermittent dizziness was associated with pathology of the vertebral and basilar arteries. However, clinical symptoms of subclavian steal syndrome were rare.

Conclusion. This case series shows that the clinical neurological course of Takayasu arteritis on treatment is benign in most cases despite the severe vascular involvement.

Keywords: Takayasu arteritis; Vasculitis; Stroke; Cerebral ischaemia; Sonography; MRI.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Ann. Thorac. Surg.Home page
E. T. Boti and E. O. Coto
Reply.
Ann. Thorac. Surg., May 1, 2006; 81(5): 1943 - 1944.
[Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.