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Rheumatology Advance Access published online on May 27, 2007
Rheumatology, doi:10.1093/rheumatology/kem120
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© The Author 2007. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Ultrasonography is a sensitive tool for monitoring localized scleroderma

S. C. Li1,2, M. S. Liebling3 and K. A. Haines1,2

1Department of Pediatrics, Joseph M. Sanzari Children's Hospital, Hackensack University Medical Center, 2Department of Pediatrics, University of Medicine and Dentistry of New Jersey, NJ and 3Department of Radiology, Hackensack University Medical Center, Hackensack, NJ, USA.

Correspondence to: S. C. Li, Joseph M. Sanzari Children's Hospital, Hackensack University Medical Center, 30 Prospect Avenue, Imus 365, Hackensack, NJ 07601, USA. E-mail: sli{at}humed.com


  Abstract

Objective. To examine the usefulness of ultrasonography (USG) for monitoring paediatric localized scleroderma (LS).

Methods. A retrospective chart review of six paediatric patients who had USG of their LS.

Results. USG detected several abnormalities in active lesions including increased blood flow, increased echogenicity and loss of subcutaneous fat. USG findings corresponded with clinical assessment, and documented regeneration of subcutaneous fat and reduction in lesion size during treatment. In one patient, USG was more sensitive than magnetic resonance evaluation.

Conclusion. USG was found to be a sensitive tool for assessing the activity and extent of LS lesions in paediatric patients. Further studies are needed to assess its general applicability for monitoring these patients.

KEY WORDS: Localized scleroderma, Ultrasonography, Paediatric, Treatment, Monitoring

Submitted 12 January 2007; revised version accepted 30 March 2007.
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