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Rheumatology Advance Access published online on February 27, 2008
Rheumatology, doi:10.1093/rheumatology/ken043
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Elevation of alkaline phosphatase in a pregnant patient with antiphospholipid syndrome: HELLP syndrome or not?

C. Delluc1, N. Costedoat-Chalumeau1, D. Saadoun1, D. Vauthier-Brouzes2, B. Wechsler1 and J.-C. Piette1

1Université Pierre et Marie Curie-Paris 6, Assistance Publique-Hôpitaux de Paris, Hôpital Pitié-Salpêtrière, Centre de Référence National pour le Lupus Systémique et le Syndrome des Antiphospholipides, Service de Médecine Interne and 2Assistance Publique-Hôpitaux de Paris, Hôpital Pitié-Salpêtrière, Service de Gynécologie Obstétrique, Paris, France.

Correspondence to: N. Costedoat-Chalumeau, AP-HP, Service de Médecine Interne, Centre de Référence National pour le Lupus Systémique et le Syndrome des Antiphospholipides, Centre Hospitalier Universitaire Pitié-Salpêtrière, 47-83 Boulevard de l’Hôpital, 75651 Paris Cedex 13, France E-mail: nathalie.costedoat@psl.aphp.fr

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SIR, Pregnant patients with APS may develop HELLP syndrome (haemolysis; elevated liver enzymes; low platelet count) that can manifest first by elevation of ALP level. However, other causes of ALP elevation must be discussed and include elevation of ALP of placental origin. We report for the first time an APS pregnant . . . [Full Text of this Article]


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