Rheumatology Advance Access published online on March 19, 2008
Rheumatology, doi:10.1093/rheumatology/ken087
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© The Author 2008. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Gout and nodal osteoarthritis: a case–control study
Academic Rheumatology, University of Nottingham, Nottingham, UK
Correspondence to:
E. Roddy, Primary Care Musculoskeletal Research Centre, Primary Care Sciences, Keele University, Staffordshire ST5 5BG, UK. E-mail: e.roddy@cphc.keele.ac.uk
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SIR, The characteristic pattern of joint involvement seen in gout has been attributed to the readiness of MSU crystals to form in osteoarthritic joints [1, 2]. In a recent community-based study, we found that joints that had been sites of acute attacks of gout are frequently also affected by OA [3] suggesting that OA predisposes to local MSU crystal deposition at individual joint sites. However, it is also possible that a general cartilage defect, such as may