Rheumatology

Acknowledgements

George Nuki and Gordon Duff

Acknowledgements
Rheumatology 1985 XXIV: ix; doi:10.1093/rheumatology/XXIV.suppl_1.ix [PDF] [Request Permissions]  

List of Participants and Authors

List of Participants and Authors
Rheumatology 1985 XXIV: v-viii; doi:10.1093/rheumatology/XXIV.suppl_1.v [PDF] [Request Permissions]  

Introduction

G. Nuki and G. W. Duff

Introduction
Rheumatology 1985 XXIV: xi-xii; doi:10.1093/rheumatology/XXIV.suppl_1.xi [PDF] [Request Permissions]  

Invited Reviews

Get checked abstract E. Atkins

Fever: Historical Perspectives and Evolution of Modern Views
Rheumatology 1985 XXIV: 1-5; doi:10.1093/rheumatology/XXIV.suppl_1.1 [Abstract] [PDF] [Request Permissions]  

Get checked abstract P.A. Murphy

The Biochemistry of Interleukin-1
Rheumatology 1985 XXIV: 6-9; doi:10.1093/rheumatology/XXIV.suppl_1.6 [Abstract] [PDF] [Request Permissions]  

Get checked abstract S. Durum

Interleukin-1 in the Immune Response and the Role of Ia Molecules in Interleukin-1 Production
Rheumatology 1985 XXIV: 10-11; doi:10.1093/rheumatology/XXIV.suppl_1.10 [Abstract] [PDF] [Request Permissions]  

Get checked abstract G.W. Duff

Interleukin-1 and Fever
Rheumatology 1985 XXIV: 12-14; doi:10.1093/rheumatology/XXIV.suppl_1.12 [Abstract] [PDF] [Request Permissions]  

Get checked abstract J.M. Dayer

Mononuclear Cell Factor—Interleukin-1 in Rheumatoid Arthritis
Rheumatology 1985 XXIV: 15-20; doi:10.1093/rheumatology/XXIV.suppl_1.15 [Abstract] [PDF] [Request Permissions]  

Get checked abstract J.T. Whicher

Interleukin-1 and Acute Phase Proteins
Rheumatology 1985 XXIV: 21-24; doi:10.1093/rheumatology/XXIV.suppl_1.21 [Abstract] [PDF] [Request Permissions]  

Get checked abstract M.E.J. Billingham

Interleukin-1: Its Relevance to Rheumatoid Arthritis
Rheumatology 1985 XXIV: 25-28; doi:10.1093/rheumatology/XXIV.suppl_1.25 [Abstract] [PDF] [Request Permissions]  

Get checked abstract G.P. Lewis and D. Gordon

Cytokines as Potential Targets for Anti-Rheumatic Therapy: A Pharmacologist's View
Rheumatology 1985 XXIV: 29-33; doi:10.1093/rheumatology/XXIV.suppl_1.29 [Abstract] [PDF] [Request Permissions]  

Get checked abstract C.A. Dinarello

Interleukin-1: Prospects for Biology
Rheumatology 1985 XXIV: 34-37; doi:10.1093/rheumatology/XXIV.suppl_1.34 [Abstract] [PDF] [Request Permissions]  

Submitted Papers: Biochemical and Molecular Aspects

Get checked abstract J. Ihrie and D.D. Wood

Molecular Heterogeneity of Human Interleukin-1: Biochemical Characterization
Rheumatology 1985 XXIV: 38-41; doi:10.1093/rheumatology/XXIV.suppl_1.38 [Abstract] [PDF] [Request Permissions]  

Get checked abstract E.S. Kimball, J.L. Rossio, and C.A. Dinarello

Absence of Pyrogenicity by Urinary IL-1 Activity
Rheumatology 1985 XXIV: 42-46; doi:10.1093/rheumatology/XXIV.suppl_1.42 [Abstract] [PDF] [Request Permissions]  

Get checked abstract J. Saklatvala and S.J. Sarsfield

Purification of PIG IL-1 (Catabolin) and Its Ability to Cause Cartilage Proteoglycan Resorption
Rheumatology 1985 XXIV: 47-51; doi:10.1093/rheumatology/XXIV.suppl_1.47 [Abstract] [PDF] [Request Permissions]  

Get checked abstract J. Saklatvala and S.J. Sarsfield

A Basic Protein from Pig Mononuclear Leucocytes that Causes Cartilage to Resorb its Proteoglycan
Rheumatology 1985 XXIV: 52-54; doi:10.1093/rheumatology/XXIV.suppl_1.52 [Abstract] [PDF] [Request Permissions]  

Get checked abstract P.R. Elford, H.J. Richardson, R.M. Sharrard, J.E. Meats, H. Skjodt, R. A. D. Bunning, A. Crawford, and R. G. G. Russell

Mononuclear Cell Factor and Synovial Factor are Closely Related to, or Identical with, Interleukin-1
Rheumatology 1985 XXIV: 55-58; doi:10.1093/rheumatology/XXIV.suppl_1.55 [Abstract] [PDF] [Request Permissions]  

Get checked abstract C. A. Dinarello, H. A. Bernheim, J. G. Cannon, G. Lopreste, S. J. C. Warner, A. C. Webb, and P. E. Auron

Purified, ³⁵S-Met, ³H-Leu-Labelled Human Monocyte Interleukin-1 (IL-1) with Endogenous Pyrogen Activity
Rheumatology 1985 XXIV: 59-64; doi:10.1093/rheumatology/XXIV.suppl_1.59 [Abstract] [PDF] [Request Permissions]  

Get checked abstract P.J. Knudsen and T.B. Strom

Elevated Intracellular cAMP Levels Inhibit Interleukin-1 Production by the Tumour Cell Line U937
Rheumatology 1985 XXIV: 65-67; doi:10.1093/rheumatology/XXIV.suppl_1.65 [Abstract] [PDF] [Request Permissions]  

Get checked abstract J. Saklatvala, S.J. Sarsfield, and D.D. Wood

An Antiserum to PIG IL-1 (Catabolin) Reacts with the Acidic But Not the Neutral Form of Human IL-1
Rheumatology 1985 XXIV: 68-71; doi:10.1093/rheumatology/XXIV.suppl_1.68 [Abstract] [PDF] [Request Permissions]  

Get checked abstract J. van Damme, M. de Ley, J. van Beeumen, G. Opdenakker, J.-M. Dayer, A. Billiau, and P. de Somer

The Interferon-Inducing 22k Protein from Human Leucocytes: Amino Acid Sequence and Identity with Interleukin-1
Rheumatology 1985 XXIV: 72-76; doi:10.1093/rheumatology/XXIV.suppl_1.72 [Abstract] [PDF] [Request Permissions]  

Get checked abstract S. Demczuk, B. Mach, and J.-M. Dayer

Differential Expression of Messenger RNAs for Mononuclear Cell Factor from Stimulated Human Monocyte-macrophage Cultures
Rheumatology 1985 XXIV: 77-81; doi:10.1093/rheumatology/XXIV.suppl_1.77 [Abstract] [PDF] [Request Permissions]  

Get checked abstract A. C. Webb, P. E. Auron, L. J. Rosenwasser, S. F. Mucci, A. Rich, S. M. Wolff, and C. A. Dinarello

Isolation and Characterization of Human Interleukin-1 mRNA by Molecular Cloning
Rheumatology 1985 XXIV: 82-86; doi:10.1093/rheumatology/XXIV.suppl_1.82 [Abstract] [PDF] [Request Permissions]  

Reports and Overviews

E.S. Kimball

Biochemical Heterogeneity of Interleukin-1
Rheumatology 1985 XXIV: 87-88; doi:10.1093/rheumatology/XXIV.suppl_1.87 [PDF] [Request Permissions]  

J. Saklatvala

Biochemical and Molecular Aspects of Interleukin-1
Rheumatology 1985 XXIV: 89-90; doi:10.1093/rheumatology/XXIV.suppl_1.89 [PDF] [Request Permissions]  

Interleukin-1 and the Immune System

Get checked abstract E. Atkins

Suppression of In Vitro Antigen-Induced Release of Interleukin-1 by Spleen Cells
Rheumatology 1985 XXIV: 91-93; doi:10.1093/rheumatology/XXIV.suppl_1.91 [Abstract] [PDF] [Request Permissions]  

Get checked abstract G. W. Duff, O. Forre, K. Waalen, E. Dickens, and G. Nuki

Rheumatoid Arthritis Synovial Dendritic Cells Produce Interleukin-1
Rheumatology 1985 XXIV: 94-97; doi:10.1093/rheumatology/XXIV.suppl_1.94 [Abstract] [PDF] [Request Permissions]  

Get checked abstract T.S. Kupper and D.R. Green

In Vivo Exposure to IL-1 or ETAF Causes Loss of Antigen-Presenting Cell Function
Rheumatology 1985 XXIV: 98-101; doi:10.1093/rheumatology/XXIV.suppl_1.98 [Abstract] [PDF] [Request Permissions]  

Get checked abstract M. Feldmann, G. Essery, M. Londei, P. Austin, J. Trowsdale, W. Bodmer, and J.R. Lamb

Role of IL-1 in the Activation and Inactivation of Human T-Cell Clones: Relevance to Rheumatological Disease
Rheumatology 1985 XXIV: 102-104; doi:10.1093/rheumatology/XXIV.suppl_1.102 [Abstract] [PDF] [Request Permissions]  

Get checked abstract D.R. Green, B. Chue, T.A. Ferguson, K.D. Beaman, and P.M. Flood

Production of an Antigen-Specific Component of Suppressor Inducer Factor by a Helper T-Cell Clone: Possible Role for IL-1 at the Interface of Immunity and Tolerance
Rheumatology 1985 XXIV: 105-111; doi:10.1093/rheumatology/XXIV.suppl_1.105 [Abstract] [PDF] [Request Permissions]  

Report and Overview

S. Durum

Interleukin-1 and the Immune System
Rheumatology 1985 XXIV: 112; doi:10.1093/rheumatology/XXIV.suppl_1.112 [PDF] [Request Permissions]  

Effects on Muscle Bone and Cartilage Connective Tissue

Get checked abstract G.H.A. Clowes, Jr., B.C. George, and L.M. Bigatello

Regulation of Protein Metabolism by ‘Proteolysis Inducing Factor’ (PIF), the Stable Circulating Fragment of Interleukin-1
Rheumatology 1985 XXIV: 113-117; doi:10.1093/rheumatology/XXIV.suppl_1.113 [Abstract] [PDF] [Request Permissions]  

Get checked abstract R.A.D. Bunning, P.R. Elford, J.E. Meats, H.J. Richardson, and R.G.G. Russell

The Effects of Mononuclear Cell Factor/Interleukin-1 on the Plasminogen Activators Produced by Human Chondrocytes
Rheumatology 1985 XXIV: 118-121; doi:10.1093/rheumatology/XXIV.suppl_1.118 [Abstract] [PDF] [Request Permissions]  

Get checked abstract H.A. Bernheim and C.A. Dinarello

Effects of Purified Human Interleukin-1 on the Release of Prostaglandin E² from Fibroblasts
Rheumatology 1985 XXIV: 122-127; doi:10.1093/rheumatology/XXIV.suppl_1.122 [Abstract] [PDF] [Request Permissions]  

Get checked abstract J. Schnyder and T. Payne

Effect of Interleukin-1 and 2 on Enzyme Secretion and Prostaglandin Fromation by Chondrocytes
Rheumatology 1985 XXIV: 128-132; doi:10.1093/rheumatology/XXIV.suppl_1.128 [Abstract] [PDF] [Request Permissions]  

Get checked abstract W.P. Arend, F.G. Joslin, and R.J. Massoni

Human Interleukin-1 Stimulation of Collagenase Production in Rabbit Articular Chondrocytes
Rheumatology 1985 XXIV: 133-135; doi:10.1093/rheumatology/XXIV.suppl_1.133 [Abstract] [PDF] [Request Permissions]  

Get checked abstract J.K. Heath, J. Saklatvala, M.C. Meikle, S.J. Atkinson, and J.J. Reynolds

Periosteal Fibroblasts Synthesize a Cytokine That Stimulates Bone Resorption and Demonstrates Interleukin-1 Activity After Partial Purification
Rheumatology 1985 XXIV: 136-139; doi:10.1093/rheumatology/XXIV.suppl_1.136 [Abstract] [PDF] [Request Permissions]  

Get checked abstract B.M. Thomson, J. Saklatvala, and T.J. Chambers

The Effects of Pig Interleukin-1 (catabolin) on Bone Resorption by Osteoclasts Disaggregated From Rat Bone
Rheumatology 1985 XXIV: 140-142; doi:10.1093/rheumatology/XXIV.suppl_1.140 [Abstract] [PDF] [Request Permissions]  

Get checked abstract A.K. Bhalla, E.P. Amento, and S.M. Krane

Effects of 1,25-Dihydroxyvitamin D³ on Interleukin-1 Production by the Human Monocyte Cell Line U937 and Peripheral Blood Monocytes
Rheumatology 1985 XXIV: 143-146; doi:10.1093/rheumatology/XXIV.suppl_1.143 [Abstract] [PDF] [Request Permissions]  

Get checked abstract M. Gowen, D.D. Wood, G.R. Mundy, and R.G.G. Russell

Studies on the Actions of Interleukin-1 on Bone Metabolism: IL-1 Stimulation of Bone Cell Proliferation, and Inhibition of IL-1 Induced Bone Resorption by Interferon-
Rheumatology 1985 XXIV: 147-149; doi:10.1093/rheumatology/XXIV.suppl_1.147 [Abstract] [PDF] [Request Permissions]  

Get checked abstract J.A. Tyler and J. Saklatvala

Pig Interleukin-1 (catabolin) Induces Resorption of Cartilage Proteoglycan and Prevents Synthesis of Proteoglycan and Collagen
Rheumatology 1985 XXIV: 150-155; doi:10.1093/rheumatology/XXIV.suppl_1.150 [Abstract] [PDF] [Request Permissions]  

Get checked abstract R.W. Jubb and J. Saklatvala

Effects of Pig IL-1 (catabolin) on Human Articular Chondrocytes
Rheumatology 1985 XXIV: 156-157; doi:10.1093/rheumatology/XXIV.suppl_1.156 [Abstract] [PDF] [Request Permissions]  

Get checked abstract J.A. Gallagher, J.N. Beresford, J.P. Dillon, H.J. Richardson, D.D. Wood, and R.G.G. Russell

The Effects of Mononuclear Cell Factor(MCF) and Interleukin-1 (IL-1) on Synthesis of Matrix by Skeletal and Articular Cells In Vitro
Rheumatology 1985 XXIV: 158-161; doi:10.1093/rheumatology/XXIV.suppl_1.158 [Abstract] [PDF] [Request Permissions]  

Get checked abstract M. Horowitz, R. Baron, J. Mart, M. Andreoli, and A. Vignery

Osteoclast Activating Factor is Distinct from the Monokine IL-1
Rheumatology 1985 XXIV: 162-164; doi:10.1093/rheumatology/XXIV.suppl_1.162 [Abstract] [PDF] [Request Permissions]  

Get checked abstract H. Skjodt, A. Crawford, P.R. Elford, E. Ihrie, D.D. Wood, and R.G.G. Russell

Cyclosporin a Modulates Interleukin-1 Activity on Bone In Vitro
Rheumatology 1985 XXIV: 165-169; doi:10.1093/rheumatology/XXIV.suppl_1.165 [Abstract] [PDF] [Request Permissions]  

Reports and Overviews

M. Gowen

Interleukin-1 Effects on Connective Tissue and Muscle
Rheumatology 1985 XXIV: 170-172; doi:10.1093/rheumatology/XXIV.suppl_1.170 [PDF] [Request Permissions]  

G. Nuki

The Effects of Interleukin-1 on Cartilage and Bone
Rheumatology 1985 XXIV: 173-174; doi:10.1093/rheumatology/XXIV.suppl_1.173 [PDF] [Request Permissions]  

Sources, Inducers and Biological actions of Interleukin-1: Clinical and Physiological Effects

Get checked abstract W.P. Arend, F.G. Joslin, and R.J. Massoni

Stimulation of Production of Interleukin-1 and an Interleukin-1 Inhibitor in Human Monocytes
Rheumatology 1985 XXIV: 175-178; doi:10.1093/rheumatology/XXIV.suppl_1.175 [Abstract] [PDF] [Request Permissions]  

Get checked abstract Y. Townsend, R.F. Hellon, W.I. Cranston, and J. Saklatvala

The Pyrogenic Properties of Catabolin
Rheumatology 1985 XXIV: 179-181; doi:10.1093/rheumatology/XXIV.suppl_1.179 [Abstract] [PDF] [Request Permissions]  

Get checked abstract G. Riveau, M. Parant, C. Damais, and L. Chedid

Role of Pyrogenic Interleukin-1 in MDP-Induced Hypoferraemia and Hypercupraemia in the Rabbit
Rheumatology 1985 XXIV: 182-185; doi:10.1093/rheumatology/XXIV.suppl_1.182 [Abstract] [PDF] [Request Permissions]  

Get checked abstract S.C. Gilman

The Roles of Interleukins-1 and 2 in Splenic T-Cell Dysfunction in Rats with Adjuvant-Induced Arthritis
Rheumatology 1985 XXIV: 186-190; doi:10.1093/rheumatology/XXIV.suppl_1.186 [Abstract] [PDF] [Request Permissions]  

Get checked abstract A.M.E. Nouri, G.S. Panayi, S.M. Goodman, and A.P.W. Waugh

Cytokines in Rheumatoid Arthritis: Production of IL-1
Rheumatology 1985 XXIV: 191-196; doi:10.1093/rheumatology/XXIV.suppl_1.191 [Abstract] [PDF] [Request Permissions]  

Get checked abstract S.J. Leibovich and P.J. Polverini

Partial Purification of Macrophage-Derived Growth Factor (MDGF) and Macrophage-Derived Angiogenic Activity (MDAA) by Gel Filtration High-Pressure Liquid Chromatography
Rheumatology 1985 XXIV: 197-202; doi:10.1093/rheumatology/XXIV.suppl_1.197 [Abstract] [PDF] [Request Permissions]  

Get checked abstract A.D. Woolf, A.M.E. Nouri, P. Woo, M.B. Richter, G.S. Panayi, and T. Gibson

Interleukin-1 and the Acute Phase Response in Acute Crystal Synovitis
Rheumatology 1985 XXIV: 203-208; doi:10.1093/rheumatology/XXIV.suppl_1.203 [Abstract] [PDF] [Request Permissions]  

Get checked abstract A. Fleck, M.A. Myers, and V. Nagendran

The Time Course of the Acute Phase Response in Man After Surgery: Contrast with Exercise
Rheumatology 1985 XXIV: 209-212; doi:10.1093/rheumatology/XXIV.suppl_1.209 [Abstract] [PDF] [Request Permissions]  

Get checked abstract C.W. Hutton, J.T. Whicher, and P.A. Dieppe

The Systemic Response to Different Stimuli in Rheumatic Diseases
Rheumatology 1985 XXIV: 213-215; doi:10.1093/rheumatology/XXIV.suppl_1.213 [Abstract] [PDF] [Request Permissions]  

Get checked abstract J.T. Whicher, A.M. Bell, C. Westacott, C.W. Hutton, and P.A. Dieppe

Decreased Production of Leucocytic Endogenous Mediator with Normal Production of B-Cell Activating Factor by Leucocytes from Patients with Systemic Sclerosis
Rheumatology 1985 XXIV: 216-219; doi:10.1093/rheumatology/XXIV.suppl_1.216 [Abstract] [PDF] [Request Permissions]  

Get checked abstract L.L. Moldawer, K.J. Hamawy, B.R. Bistrian, M. Georgieff, M. Drabik, C.A. Dinarello, and G.L. Blackburn

A Therapeutic use for Interleukin-1 in the Protein-Depleted Animal
Rheumatology 1985 XXIV: 220-223; doi:10.1093/rheumatology/XXIV.suppl_1.220 [Abstract] [PDF] [Request Permissions]  

Effects on Muscle, Bone and Cartilage Connective Tissue

Get checked abstract D. Gordon, M.L. Barrett, and G.P. Lewis

Effects of Exogenous Cytokines on the Antilymphoproliferative Effects of Auranofin and Sodium Autothiomalate
Rheumatology 1985 XXIV: 224-225; doi:10.1093/rheumatology/XXIV.suppl_1.224 [Abstract] [PDF] [Request Permissions]  

Get checked abstract J.G. Cannon and C.A. Dinarello

Multiple Interleukin-1 Activities in Luteal Phase Human Plasma
Rheumatology 1985 XXIV: 226-229; doi:10.1093/rheumatology/XXIV.suppl_1.226 [Abstract] [PDF] [Request Permissions]  

Reports and Overviews

G.W. Duff

Sources, Inducers and Clinical Effects of Interleukin-1
Rheumatology 1985 XXIV: 230; doi:10.1093/rheumatology/XXIV.suppl_1.230 [PDF] [Request Permissions]  

J.T. Whicher

Acute Phase Response, Blood Levels and Therapeutic Potential of Interleukin-1
Rheumatology 1985 XXIV: 231; doi:10.1093/rheumatology/XXIV.suppl_1.231 [PDF] [Request Permissions]  

G.W. Duff and G. Nuki

Closing Comments
Rheumatology 1985 XXIV: 232; doi:10.1093/rheumatology/XXIV.suppl_1.232 [PDF] [Request Permissions]  

G. Nuki and G.W. Duff

Editors' Postscript
Rheumatology 1985 XXIV: 233-234; doi:10.1093/rheumatology/XXIV.suppl_1.233 [PDF] [Request Permissions]  

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